Alzheimer’s Disease Neuroimaging Initiative Selected Research

Dementia (Dementias)

11/2022	Introducing a gatekeeping system for amyloid status assessment in mild cognitive impairment.
11/2022	The impact of subthreshold levels of amyloid deposition on conversion to dementia in patients with amyloid-negative amnestic mild cognitive impairment.
9/2022	Assessing the Clinical Meaningfulness of the Alzheimer's Disease Composite Score (ADCOMS) Tool.
8/2022	Genome-wide association study identifies APOE locus influencing plasma p-tau181 levels.
5/2022	Biomarker A+T-: is this Alzheimer's disease or not? A combined CSF and pathology study.
1/2022	Association of CSF Aβ38 Levels With Risk of Alzheimer Disease-Related Decline.
1/2022	Grey matter network markers identify individuals with prodromal Alzheimer's disease who will show rapid clinical decline.
1/2022	Plasma β-Amyloid in Mild Behavioural Impairment - Neuropsychiatric Symptoms on the Alzheimer's Continuum.
1/2022	A Novel Panel of Plasma Proteins Predicts Progression in Prodromal Alzheimer's Disease.
1/2022	The Trajectory of Cerebrospinal Fluid Growth-Associated Protein 43 in the Alzheimer's Disease Continuum: A Longitudinal Study.

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Alzheimer’s Disease Neuroimaging Initiative Research Topics

Disease

467	Alzheimer Disease (Alzheimer's Disease) 11/2022 - 09/2010
272	Cognitive Dysfunction 11/2022 - 09/2010
128	Dementia (Dementias) 11/2022 - 01/2012
91	Atrophy 04/2022 - 01/2012
48	Disease Progression 10/2022 - 01/2012
21	Neurodegenerative Diseases (Neurodegenerative Disease) 08/2022 - 10/2016
12	Amyloidosis 01/2022 - 01/2015
7	Genetic Risk Score 01/2022 - 01/2017
7	Tauopathies 01/2022 - 01/2017
7	Amyloid Plaque 01/2022 - 12/2012
6	Neuroinflammatory Diseases 01/2022 - 01/2015
6	Inflammation (Inflammations) 01/2022 - 01/2020
6	Prodromal Symptoms 02/2020 - 07/2014
5	Parkinson Disease (Parkinson's Disease) 05/2022 - 01/2013
5	Cerebral Cortical Thinning 02/2022 - 09/2015
4	Genetic Predisposition to Disease (Genetic Predisposition) 01/2020 - 01/2017
4	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2020 - 01/2017
3	Traumatic Brain Injuries (Traumatic Brain Injury) 02/2022 - 08/2017
3	Hypertension (High Blood Pressure) 01/2022 - 01/2015
3	Proteostasis Deficiencies 01/2021 - 01/2017
3	Infarction (Infarctions) 01/2020 - 10/2011
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2019
2	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2022 - 01/2021
2	Pathologic Processes 01/2022 - 10/2019
2	Frailty 01/2021 - 01/2020
2	Weight Loss (Weight Reduction) 01/2020 - 01/2018
2	Brain Injuries (Brain Injury) 02/2019 - 11/2015
2	Insulin Resistance 01/2018 - 01/2017
2	Prostatic Neoplasms (Prostate Cancer) 01/2017 - 01/2016
1	Clinical Deterioration 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022

Drug/Important Bio-Agent (IBA)

286	Biomarkers (Surrogate Marker)IBA 10/2022 - 09/2010
248	Amyloid (Amyloid Fibrils)IBA 11/2022 - 10/2011
84	Apolipoproteins E (ApoE)IBA 09/2022 - 03/2012
40	Glucose (Dextrose)FDA LinkGeneric 10/2022 - 12/2012
39	ApolipoproteinsIBA 04/2022 - 06/2012
34	florbetapirIBA 10/2021 - 01/2013
32	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2011
28	Biological ProductsIBA 05/2022 - 01/2012
28	Amyloid beta-PeptidesIBA 04/2022 - 12/2012
19	Apolipoprotein E4IBA 01/2022 - 01/2015
15	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 01/2022 - 01/2019
15	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2021 - 02/2013
10	tau Proteins (tau Protein)IBA 01/2022 - 01/2018
9	Pharmaceutical PreparationsIBA 01/2022 - 02/2012
7	Peptides (Polypeptides)IBA 07/2021 - 01/2012
5	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 01/2022 - 01/2020
5	Complement System Proteins (Complement)IBA 01/2022 - 01/2016
5	NeurograninIBA 01/2022 - 11/2015
5	SynucleinsIBA 11/2020 - 01/2013
5	Cholinergic Agents (Cholinergics)IBA 01/2020 - 12/2016
4	LipidsIBA 01/2022 - 10/2013
4	Insulin-Like Growth Factor Binding Protein 2IBA 01/2022 - 01/2013
4	CholesterolIBA 01/2022 - 05/2012
4	Indicators and Reagents (Reagents)IBA 11/2020 - 10/2016
3	Blood Proteins (Serum Proteins)IBA 01/2022 - 10/2013
3	Threonine (L-Threonine)FDA Link 12/2021 - 01/2021
3	EnzymesIBA 10/2019 - 01/2016
3	Blood Glucose (Blood Sugar)IBA 01/2019 - 01/2017
3	HomocysteineIBA 01/2018 - 01/2015
3	LeptinIBA 01/2018 - 01/2013
3	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 10/2014 - 01/2012
2	IronIBA 01/2022 - 01/2017
2	AZD4694IBA 10/2021 - 01/2021
2	Antidepressive Agents (Antidepressants)IBA 01/2021 - 01/2018
2	Messenger RNA (mRNA)IBA 01/2021 - 01/2018
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 11/2020
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2021 - 11/2020
2	RadiopharmaceuticalsIBA 01/2021 - 03/2020
2	PrionsIBA 01/2021 - 10/2020
2	AdiponectinIBA 01/2021 - 01/2020
2	Genetic Markers (Genetic Marker)IBA 01/2021 - 01/2015
2	FibrinIBA 01/2020 - 01/2016
2	LigandsIBA 01/2020 - 01/2020
2	Sex Hormone-Binding GlobulinIBA 01/2020 - 01/2017
2	Pemetrexed (MTA)FDA Link 09/2019 - 12/2017
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2019 - 01/2018
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019 - 09/2015
2	Carrier Proteins (Binding Protein)IBA 05/2018 - 10/2013
2	Insulin-Like PeptidesIBA 01/2018 - 12/2017
2	Testosterone (Sustanon)FDA Link 01/2018 - 01/2017
2	Insulin (Novolin)FDA Link 01/2018 - 01/2013
2	CytokinesIBA 11/2016 - 01/2013
2	Cerebrospinal Fluid ProteinsIBA 01/2015 - 09/2014
1	Valine (L-Valine)FDA Link 08/2022
1	rho GTPase-activating proteinIBA 05/2022
1	Apolipoproteins B (ApoB)IBA 01/2022
1	florbenazine F 18IBA 01/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	Phosphotransferases (Kinase)IBA 01/2022
1	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 01/2022
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 01/2022
1	GAP-43 Protein (GAP 43 Protein)IBA 01/2022
1	Interleukin-3 (Interleukin 3)IBA 01/2022
1	Ferritins (Ferritin)IBA 01/2022
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 01/2022
1	Interleukin-8 (Interleukin 8)IBA 01/2022

Therapy/Procedure

11	Therapeutics 03/2022 - 01/2012
7	Activities of Daily Living (ADL) 11/2022 - 01/2017
3	Secondary Prevention 08/2022 - 01/2018